SONAR

The SONAR registry (Spastic Dystonia Registry) is a non-interventional observational study focused on patients with first acute ischaemic stroke of the carotid circulation with permanent neurological deficit. Study objectives involve monitoring of spasticity incidence and prevalence rates, assessment of potential risk factors, and analysis of mortality rates. Furthermore, the project will provide a database background and a pilot version of the information system for the monitoring of treatment burden, results and quality in clinical practice in Czech stroke centres.

Patients are included based on inclusion criteria, and are characterised according to the presence or absence of exposition to potential risk factors at the beginning of the study (primary stroke – examination during the first check-up). Repeated check-ups make it possible to gather data for the assessment of spasticity incidence rates and for the comparison of various groups of patients according to their risk factors.

Project objectives:

• assessent of spasticity incidence and prevalence rates at the time of 12 months after the primary stroke,
• analysis and quantification of association between potential risk factors and the risk of development of spasticity and clinically significant spasticity,
• assessment of spasticity rates after the primary stroke for catchment areas of Czech stroke centres,
• analysis of mortality rates in the followed-up cohort of patients,
• development of a database background and a pilot version of the information system for the monitoring of treatment burden, results and quality in clinical practice in Czech stroke centres.

Other important information:

• Partners: three Czech clinical centres dealing with stroke treatment (you can find more detailed information – in Czech language only – on the website of the SONAR project)
• Brief overview of results: you can find more detailed information – in Czech language only – on the website of the SONAR project